Treatment and Prevention

Drug Lipantil: instructions for use

Lipantil is a medicine with which patients can get rid of such disorders in the functioning of the body as hypercholesterolemia.

International non-proprietary name

Fenofibrate.

The drug helps to get rid of such disorders in the functioning of the body, such as hypercholesterolemia.

ATX

C10AB05.

Forms of release and composition

You can buy the drug only in one dosage form. These are capsules, each containing 200 mg of micronized fenofibrate.

pharmachologic effect

The drug belongs to the means with lipid-lowering action. The active substance stimulates lipolysis and the elimination of atherogenic lipoproteins from the blood plasma, which contain a large amount of triglycerides.

Fenofibrate reduces the amount of lipids in the patient's body. Thanks to the use of the drug, the total cholesterol and triglyceride concentrations are also reduced.

Patients diagnosed with dyspidemia and hyperuricemia, may note the effect of the drug on the uric acid content in the blood. The level is reduced by about 25%. Due to the use of the drug, the amount of low-density lipoproteins is reduced. This is especially important for patients who are diagnosed with coronary heart disease (with her, the number of LDL is elevated). The amount of HDL cholesterol (high density) is increasing.

The drug belongs to the means with lipid-lowering action.

Pharmacokinetics

The presence of parental fenofibrate is not fixed in the patient's plasma. Fenofibric acid is the main metabolite that is formed as a result of decomposition reactions. It binds albumin at 99%.

The maximum concentration of the drug in the blood is noted 4-5 hours after ingestion. The level of active substance in the plasma remains relatively stable even in the case of prolonged administration. When taking medication with food, the degree of absorption increases.

The half-life of the drug is approaching 20 hours. The active substance is excreted by the kidneys. Hemodialysis is not eliminated from the body.

Indications for use

It is necessary to carry out therapy by means of detecting hypercholesterolemia and hypertriglyceridemia in a person in which diet, hygiene and physical activity do not have the desired effect.

Contraindications

There are such conditions when it is impossible to treat with this medication. These include the following cases:

  • pathology of the gallbladder;
  • phototoxicity or photosensitization in the treatment of ketoprofen or fibrates, previously identified in the patient;
  • congenital galactosemia;
  • hypersensitivity to the active substance of the drug.

You can not take the drug in the existing pathologies of the gallbladder.

Carefully

Muscle fiber pathology in the history of any family member, hypothyroidism and alcohol abuse.

How to take Lipantil

Standardly, the doctor prescribes 1 capsule of medication once a day during a meal. The duration of treatment depends on many basic data about the disease and the condition of the patient.

Most often, a long medication is necessary. In this case, the patient should not forget about the need to adhere to the diet, which followed before the start of treatment. It is important to remember about physical activity.

In the absence of efficacy of therapy, after 3 months from its onset, it is worthwhile to consult a doctor to prescribe an analogue or an additional drug.

The patient himself must read the instructions before drinking the capsules.

In the absence of efficacy of therapy, after 3 months from its onset, it is worthwhile to consult a doctor to prescribe an analogue or an additional drug.

With diabetes

It is necessary to consult with the doctor about which treatment option will be most appropriate in each individual case. The doctor will take into account the patient's age, his medical history and other factors.

Side effects of Lipantil

When influencing the cardiovascular system, venous thromboembolism may appear. If the digestive system suffers, which is not uncommon, it manifests as abdominal pain, diarrhea, flatulence, vomiting and nausea, pancreatitis, hepatitis and gallstones.

Rarely appears rhabdomyolysis (necrosis of striated muscle tissue), weakness and muscle spasms, which indicates a malfunction of the musculoskeletal system. Rhabdomyolysis is most dangerous and requires intervention from doctors. Possible negative symptoms are baldness, skin rashes and urticaria (skin irregularities), pneumopathy and headache.

In some cases, the side effect of drugs is expressed through diarrhea.
Lipantil may cause nausea and vomiting.
Among the side effects of the drug baldness.
An allergic reaction to the medication may develop.
The drug can cause headaches.
In men, sexual function may be affected during therapy.
The drug may cause abdominal pain.

In men and women, sexual function may be impaired, as a result, treatment in the field of urology and gynecology may be needed. At the age of 45 years and older will need a special approach to the patient.

There is evidence of the likelihood of changes in laboratory parameters in a patient, which include an increase in the level of hepatic transaminases, urea and serum creatinine.

Influence on ability to operate mechanisms

A negative effect on this ability can be exerted due to the fact that the patient often has a headache when taking the drug.

special instructions

Use in old age

There is no data regarding the need for dose adjustment.

Receiving the drug by elderly patients does not require dose adjustment.

Appointment to children

Since information is not provided about the safety and efficacy of the drug in the treatment of children before the age of majority, doctors do not prescribe the drug to avoid negative consequences.

Use during pregnancy and lactation

As the data confirming safety is not enough, it is not necessary to prescribe a medicine during gestation and breastfeeding of the child.

Lipantil Overdose

An antidote to the drug has not yet been found. If an overdose is suspected, supportive therapy is prescribed and symptomatic treatment is carried out. Hemodialysis is not effective.

Interaction with other drugs

The active substance of the drug can cause bleeding when taken with oral anticoagulants.

When treated with cyclosporin, the patient’s kidney function may be impaired.

When conducting therapy in conjunction with inhibitors of HMG-CoA reductase, toxic effects on the muscles can be exerted.

Compatibility with alcohol

It is important to give up alcohol for the period of treatment.

Analogs

Traykor, Fenofibrat Canon and dietary supplements.

Traykor: reviews, price, instructions for use

Pharmacy vacation terms

Can I buy without a prescription

Without a prescription to buy the drug will not work.

Price Lipantil

The cost of medication is about 1000 rubles.

Drug storage conditions

At room temperature.

Shelf life

3 years.

Manufacturer

Recitharm Fontaine, Rue des Pres Pots, 21121, Fontaine-le-Dijon, France.

The drug is released only by prescription.

Reviews Lipantila

V.N. Chernysheva, endocrinologist, Kirov: "The drug is effective in combating elevated cholesterol in the blood. This condition occurs when the patient leads a wrong lifestyle, eats fat, there is not enough sports in his daily life. In this case, it is necessary to correct such violations. "

J.N. Ganchuk, general practitioner, Yekaterinburg: “The drug has a productive effect on the level of cholesterol and triglycerides in the patient’s blood. The duration of treatment most often does not exceed the standard terms.”

Alina, 37 years old, Novosibirsk: “The drug helped when it was necessary to eliminate health problems. He was prescribed by a doctor. After she learned that it was impossible to buy medicine without a prescription from a doctor at all. the most important thing".

Kirill, 28, Zheleznogorsk: “I drank these capsules when the need arose for treating metabolic disorders. I believe that it has a positive effect on the body, since no side effects have been noticed. Basically, everything was fine, so I can definitely recommend a medicine to people who need to use it. But without coordination with the doctor, you should not start treatment, as there may be adverse health effects. "

Watch the video: What are the Side Effects of Cholesterol-Lowering Medications? (November 2019).

Loading...